As we are aware of, the fact that Diabetes is increasing exponentially across the globe. As today prevalence of Diabetes across the world is 9.3 % (463 million) people rising to 10.2 % (578 million) by 2030!
As we all know India is the capital of Diabetes. About 11% population of India is Diabetic. About 11 crore people are suffering from Type II Diabetes.
Pre diabetes is tip of the iceberg. About 15.3 % of the Indian population could be pre-Diabetic. Here we are going to discuss Why Magnesium is essential in Type II Diabetes?
Magnesium deficiency contributes to suboptimal treatment of Type II Diabetes outcome.
INSULINE RESISTANCE
HYPERGLYCEMIA
RAPID PROGRESS OF DIABETES
RAPID PROGRESS OF COMPLICATIONS
There is a vicious cycle between patients with Type II Diabetes.
Insulin resistance leads to Hypomagnesemia, which leads to more Insulin resistance
| Causes Of Hypomagnesemia In Type II Diabetes Mellitus
DIETARY INTAKE
URINARY LOSS
RENAL REABSORPTION
| Use Of Loop and Thiazide Diuretics
INTESTINAL MAGNESIUM ABSORPTION
| Use Of Aati Diabetics Like Metformin
THE BEST WAY TO REPLACE THE MAGNESIUM IS ORALLY
Oral Magnesium may improve Diabetes by
Insulin synthesis
Pancreatic insulin release
Insulin Sensitivity
Insulin Receptor Interaction
Cellular glucose transfer
Metabolism
Glycaemic control
| Dose
Magnesium is found in foods like Nuts, Leafy Vegetables, Milk and Milk-products.
Various types of magnesium supplements are available in market
Magnesium Oxide
Magnesium Gluconate
Magnesium Citrate
Magnesium Chloride
Magnesium Aspartate
Magnesium Glycinate
Out of these Magnesium Glycinate has been shown to have good absorption.
Dose of 250 mg of Magnesium supplement has been shown to improve blood glucose level..
| Possible Side Effects Of Magnesium Overdose
It is recommended to take daily Magnesium supplement more than 350 mg under medical supervision.
Though Magnesium toxicity is very rare, consumption of high dose of Magnesium may cause nausea, diarrhoea, abdominal pain.